Zachary Levi
Chuck Bartowski - 91 episoder

Yvonne Strahovski
Sarah Walker - 91 episoder

Adam Baldwin
John Casey - 91 episoder

Joshua Gomez
Morgan Grimes - 91 episoder

Sarah Lancaster
Ellie Woodcomb - 91 episoder

Ryan McPartlin
Devon Woodcomb - 88 episoder

Mark Christopher Lawrence
Big Mike - 87 episoder

Vik Sahay
Lester Patel - 78 episoder

Scott Krinsky
Jeff Barnes - 78 episoder

Bonita Friedericy
Diane Beckman - 76 episoder

Julia Ling
Anna Wu - 31 episoder

Jesse Heiman
Fernando - 31 episoder

Mekenna Melvin
Alex McHugh - 24 episoder

Michael Kawczynski
Skip - 21 episoder

Tony Hale
Emmett Milbarge - 13 episoder

Brandon Routh
Daniel Shaw - 12 episoder

Linda Hamilton
Mary Elizabeth Bartowski - 12 episoder

Tony Todd
CIA Director Graham - 10 episoder

Matt Bomer
Bryce Larkin - 7 episoder

Scott Bakula
Steve Bartowski - 7 episoder

C.S. Lee
Harry Tang - 6 episoder

Timothy Dalton
Alexei Volkoff - 6 episoder

Lauren Cohan
Vivian Volkoff - 4 episoder

Scott Holroyd
Justin Sullivan - 5 episoder

Kristin Kreuk
Hannah - 4 episoder

Jordana Brewster
Dr. Jill Roberts - 4 episoder

Mini Anden
Carina Miller - 4 episoder

Clare Carey
Kathleen McHugh - 4 episoder

Richard Burgi
Clyde Decker - 4 episoder

Carrie-Anne Moss
Gertrude Verbanski - 4 episoder

Angus Macfadyen
Nicholas Quinn - 4 episoder

Chevy Chase
Ted Roark - 3 episoder

David Burke
Mr. Mercer - 2 episoder

Patricia Rae
Bolonia Grimes - 3 episoder

Mel Fair
News Anchor - 1 episoder

Joshua Rush
Young Chuck - 3 episoder

Ray Wise
Riley - 3 episoder

Robin Givens
Jane Bentley - 3 episoder

Morgan Fairchild
Honey Woodcomb - 3 episoder

Arnold Vosloo
Vincent Smith - 3 episoder