Tom Welling
Clark Kent - 216 episoder

Allison Mack
Chloe Sullivan - 201 episoder

Kristin Kreuk
Lana Lang - 157 episoder

Michael Rosenbaum
Lex Luthor - 153 episoder

John Glover
Lionel Luthor - 143 episoder

Erica Durance
Lois Lane - 141 episoder

Annette O'Toole
Martha Kent - 135 episoder

John Schneider
Jonathan Kent - 113 episoder

Justin Hartley
Oliver Queen - 72 episoder

Sam Jones
Pete Ross - 67 episoder

Cassidy Freeman
Tess Mercer - 64 episoder

Laura Vandervoort
Kara Kent - 63 episoder

Aaron Ashmore
Jimmy Olsen - 53 episoder

Eric Johnson
Whitney Fordman - 23 episoder

Callum Blue
Zod - 22 episoder

Jensen Ackles
Jason Teague - 22 episoder

Sam Witwer
Davis Bloome - 22 episoder

Camille Mitchell
Nancy Adams - 22 episoder

Terence Stamp
Jor-El (voice) - 21 episoder

Mitchell Kosterman
Ethan Miller - 14 episoder

Alessandro Juliani
Emil Hamilton - 14 episoder

James Marsters
Milton Fine - 13 episoder

Sarah-Jane Redmond
Nell Potter - 11 episoder

Emmanuelle Vaugier
Helen Bryce - 10 episoder

Mike Dopud
Security Guard - 10 episoder

Phil Morris
John Jones - 9 episoder

Michael Cassidy
Grant Gabriel - 7 episoder

Adrian Holmes
Basqat - 4 episoder

Rekha Sharma
Dr. Harden - 7 episoder

Anna Galvin
Gina - 7 episoder

Sharon Taylor
Faora - 7 episoder

Julian Christopher
Dr. MacIntyre - 6 episoder

Ian Somerhalder
Adam Knight - 6 episoder

Bill Mondy
James Beels - 4 episoder

Robert Wisden
Gabe Sullivan - 6 episoder

Jane Seymour
Genevieve Teague - 6 episoder

Ari Cohen
Regan Matthews - 6 episoder

Tom O'Brien
Roger Nixon - 5 episoder

Patrick Cassidy
Henry Small - 5 episoder

Stephen Lobo
Randall Brady - 5 episoder