Hayden Panettiere
Claire Bennet - 78 episoder

Milo Ventimiglia
Peter Petrelli - 78 episoder

Masi Oka
Hiro Nakamura - 78 episoder

Jack Coleman
Noah Bennet - 78 episoder

Adrian Pasdar
Nathan Petrelli - 78 episoder

Ali Larter
Tracy Strauss - 44 episoder

Greg Grunberg
Matt Parkman - 78 episoder

Sendhil Ramamurthy
Mohinder Suresh - 78 episoder

James Kyson
Ando Masahashi - 78 episoder

Zachary Quinto
Gabriel 'Sylar' Gray - 70 episoder

Cristine Rose
Angela Petrelli - 63 episoder

Santiago Cabrera
Isaac Mendez - 42 episoder

Ashley Crow
Sandra Bennet - 39 episoder

Noah Gray-Cabey
Micah Sanders - 37 episoder

Jimmy Jean-Louis
The Haitian - 32 episoder

Tawny Cypress
Simone Deveaux - 23 episoder

Leonard Roberts
D.L. Hawkins - 23 episoder

Robert Knepper
Samuel Sullivan - 19 episoder

Dania Ramirez
Maya Herrera - 18 episoder

Lisa Lackey
Janice Parkman - 18 episoder

Randall Bentley
Lyle Bennet - 18 episoder

David Anders
Adam Monroe - 16 episoder

Dawn Olivieri
Lydia - 16 episoder

Brea Grant
Daphne Millbrook - 16 episoder

Adair Tishler
Molly Walker - 16 episoder

Željko Ivanek
Emile Danko - 13 episoder

George Takei
Kaito Nakamura - 13 episoder

Kristen Bell
Elle Bishop - 12 episoder

David H. Lawrence XVII
Eric Doyle - 12 episoder

Stephen Tobolowsky
Bob Bishop - 11 episoder

Madeline Zima
Gretchen Berg - 11 episoder

Thomas Dekker
Zach - 11 episoder

Malcolm McDowell
Daniel Linderman - 10 episoder

Jessalyn Gilsig
Meredith Gordon - 10 episoder

Blake Shields
Flint Gordon - 10 episoder

Jamie Hector
Benjamin 'Knox' Washington - 10 episoder

Ntare Guma Mbaho Mwine
Usutu - 10 episoder

Robert Forster
Arthur Petrelli - 10 episoder

Elisabeth Röhm
Lauren Gilmore - 9 episoder

Nora Zehetner
Eden McCain - 9 episoder