Jennifer Garner
Sydney Bristow - 105 episoder

Victor Garber
Jack Bristow - 105 episoder

Ron Rifkin
Arvin Sloane - 105 episoder

Carl Lumbly
Marcus Dixon - 105 episoder

Kevin Weisman
Marshall Flinkman - 105 episoder

Michael Vartan
Michael Vaughn - 95 episoder

Greg Grunberg
Eric Weiss - 68 episoder

David Anders
Julian Sark - 56 episoder

Bradley Cooper
Will Tippin - 46 episoder

Merrin Dungey
Francie Calfo - 36 episoder

Mía Maestro
Nadia Santos - 31 episoder

Lena Olin
Irina Derevko - 27 episoder

Melissa George
Lauren Reed - 22 episoder

Terry O'Quinn
Kendall - 18 episoder

Rachel Nichols
Rachel Gibson - 17 episoder

Amy Acker
Kelly Peyton - 17 episoder

Balthazar Getty
Thomas Grace - 17 episoder

Élodie Bouchez
Renée Rienne - 12 episoder

Patricia Wettig
Judy Barnett - 11 episoder

Kevin Sutherland
Agent Blake - 7 episoder

Amy Irving
Emily Sloane - 9 episoder

Amanda Foreman
Carrie Bowman - 8 episoder

James Handy
Arthur Devlin - 8 episoder

Sarah Shahi
Jenny - 7 episoder

Ira Heiden
C.I.A. Techie Rick McCarthy - 7 episoder

Gina Torres
Anna Espinosa - 6 episoder

Kurt Fuller
Robert Lindsey - 6 episoder

Evan Parke
Charlie Bernard - 6 episoder

Tyrees Allen
Gordon Dean - 6 episoder

Angus Scrimm
Calvin McCullough - 6 episoder

Don Took
Agent Grey - 6 episoder

Isabella Rossellini
Katya Derevko - 5 episoder

Sonia Braga
Elena Derevko - 5 episoder

Joey Slotnick
Steven Haladki - 5 episoder

Ric Young
Zhang Lee - 5 episoder

Yvonne Farrow
Diane Dixon - 5 episoder

Wolf Muser
Ramon Veloso - 5 episoder

Angela Bassett
Hayden Chase - 4 episoder

Keone Young
Professor Choy - 4 episoder

Michael Yavnielli
C.I.A. Techie - 2 episoder