Zach Braff
John 'J.D.' Dorian - 181 episoder

Donald Faison
Christopher Turk - 181 episoder

John C. McGinley
Perry Cox - 181 episoder

Ken Jenkins
Bob Kelso - 176 episoder

Sarah Chalke
Elliot Reid - 172 episoder

Neil Flynn
Janitor - 169 episoder

Judy Reyes
Carla Espinosa - 168 episoder

Robert Maschio
Todd - 127 episoder

Sam Lloyd
Ted Buckland - 94 episoder

Aloma Wright
Laverne Roberts - 89 episoder

Christa Miller
Jordan Sullivan - 88 episoder

Johnny Kastl
Doug Murphy - 50 episoder

Travis Schuldt
Keith - 40 episoder

Eliza Coupe
Denise Mahoney - 23 episoder

Charles Rahi Chun
Dr. Wen - 21 episoder

Michael Hobert
Lonnie - 15 episoder

Elizabeth Banks
Dr. Kim Briggs - 16 episoder

George Miserlis
Crispin - 15 episoder

Paul F. Perry
Randall - 15 episoder

Philip McNiven
Roy - 14 episoder

Kerry Bishé
Lucy Bennett - 13 episoder

Michael Mosley
Drew Suffin - 13 episoder

Dave Franco
Cole Aaronson - 13 episoder

Andrew Miller
Baby Jack - 13 episoder

Scott Foley
Sean Kelly - 12 episoder

Tara Reid
Danni - 11 episoder

Manley Henry
Snoop Dogg Intern - 4 episoder

Christina Miles
Gloria - 11 episoder

Nicky Whelan
Maya - 10 episoder

Heather Graham
Dr. Molly Clock - 9 episoder

Jordan Zucker
Lisa - 9 episoder

Joe Rose
Troy - 8 episoder

Martin Klebba
Randall - 8 episoder

Geoff Stevenson
Dr. Beardface - 8 episoder

Aaron Ikeda
Rex - 8 episoder

Michael Learned
Mrs. Wilk - 8 episoder

Kit Pongetti
Lady - 7 episoder

Shaughn Buchholz
Cabbage - 4 episoder

Betsy Beutler
Dr. Katie Collins - 8 episoder

Bob Clendenin
Dr. Zeltzer - 7 episoder